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ADDISON’S DISEASE (Supra-renal insufficiency)

ADDISON’S DISEASE (Supra-renal insufficiency)

Ques. 1 What is Addison’s Disease?
Ans. This is a condition characterized by asthenia, hypotension, wasting, pigmentation of skin and mucous membrane, and deranged mineral and carbohydrate metabolism due to hypo-function of the Adrenal Cortex, as a result of bilateral destruction. 

Ques. 2 What are the causes symptoms, signs and clinical features of Addison’s disease?
Ans. Causes :
a) Syphilis, hypopituitarism, leukaemia etc.
b) Malignancy.
c) Infiltrative disease, e,g. Hodgkin’s disease, Amyloidosis.
d) Prolonged cortico steroid therapy.
e) Congenital adrenal hyperplasia.

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f) Idiopathic adrenal atrophy.
g) Tuberculosis.

Clinical Features : Onsent-gradual, Age between 30 to 50 years.
Symptoms –
I. Poor concentration.
II. Hypotension.
III. Nausea, vomiting, diarrhoea, anorexia etc.
IV. Craving for salt. Weight loss (cachexia)
b) Secondary infection, e.g. pneumonia etc.
c) Hypo or hyperthyroidism or glycosuria.
Differential Diagnosis :
I. The distinction between adrenal insufficiency due to Addision’s disease and secondary to pituitary failure is that pigmentation does not occur in latter.
II. Addision’s disease is distinguished from cancer of pylorus, showing sallowness of the skin by its distinctive symptoms of low blood pressure.

Ques. 3 What is the treatment of Addison’s disease?
a) Treatment of underlying cause.
b) For crises-Rest in bed, kept warm and given 1000 to 1500 ml. of 0.9% sodium chloride and 5 to 10% dextrose solution I.V.
c) Homoeopathic remedies.
d) In mild cases addition of extra salt in the diet.
e) In moderate and severe cases-replacement therapy is required.

Ques. 4 Which medicines are good for Addison’s disease?
Ans. 1) NATRUM MUR – Great weakness and weariness, great debility, craving for salt. Greasy and oily skin and sometimes discolouration. Unquenchable thirst, amenorrhoea.
2) PHOSPHORUS – Weakness and fatigability, pigmentation of skin, fearfulness hoarseness, vomiting with loss of appetite. Thirst for very cold water sleeplessness.
3) ARGENTUM NIT – Loss of appetite, chronic wasting and diarrhoea, skin brown, tense and hard, great desire for sweets. loss of control and want of balance every where, mentally and physically.
4) ARSENICUM – Burning and discolouration of skin & mucous membrane. Nervous depression, general debility ; feeble heart action & tendency to vomit, anxious and restlessness and nightly aggravation.


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0 # Jayesh 2017-07-23
Hii, plz tell me,Which tests can confirm syphilis in primary stage, also suggest name of good maternity hospitals in Solan ?
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0 # Dr. Pooja 2017-07-24
During the primary stage,DG illumination tests are very helpful, find good maternity hospitals-Gupta Surgical Hospital and Maternity Home - Baddi.
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0 # Lakshay 2017-07-11
Hello I am from Vidisha, My neighbour has been feeling redness and burning in urethral organs, can it be a disease, should she visit gynec?
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0 # Dr. Pooja 2017-07-12
It can be a simple infection also and a disease also, If after the examination, the presence of gram negative bacteria is seen ,gonorrhoea infection can be thought of, she should visit good women's specialist- find list of Gynecologist in Vidisha
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0 # Vaibhav 2017-06-08
Hi, plz let me know What is the incubation period of Syphilis, also give me the list of good female's specialist in Mohali ?
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0 # Dr. Naresh 2017-06-09
Hii, The incubation period can be 10 to 90 days, plz find list of Gynecologist in Mohali
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0 # Aarav Older than three months
Hii, I am from Sehore, Please tell that can moisture be responsible for infections ?
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0 # Dr. Pooja Older than three months
Hello, good to see that you are from Sehore, yes,that is why u must keep your genital organs clean and dry because moisture can favour infections.
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0 # Jyoti Older than three months
Hello, I am from Mirzapur, PLz suggest some biochemic remedies for gonorrhoea .
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0 # Dr. Naresh Older than three months
Kali Mur, Natrum Mur, Natrum Sulph, and silicea are few important biochemic emedies in homoeopathy which can be used safely in this case, you can also take advise from gynecologist given here-Gynecologist in Mirzapur.
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0 # Vivaan Older than three months
Hello, plz let me know Can gonorrhoea be transmitted to small children, should I consult with good maternity doctor in Pathanamthitta
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0 # Dr. Pooja Older than three months
yes,this can be transmitted by infected mothers to children, In this case it is called as ophthalmia neonatorum, find list of good doctor-.Sovereign Gems Hospital
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