Frequently Asked Questions (FAQs) on erythropoiesis-or-blood-formation | HospitalKhoj

ERYTHROPOIESIS OR BLOOD FORMATION

ERYTHROPOIESIS OR BLOOD FORMATION

Ques. 1        Describe the stages of Erythropoiesis or how erythropiesis occurs? What factors are responsible for Erythropoleses? [discuss the role of anoxia (hypoxia) & vitamins in erythropoiesis].

Ans.             In the early embryo – Red – call formation takes place in the area vasculosa of the yolk-sac. This consists of a syncytium of branched cells. The angioblasts from plexuses. Fluid droplets appear gradually in these syncytial masses & run together. Thus a part is hollowed out to from network of capillaries at abut the 3rd week of intra-uterine life. The remains of syncytial masses persist as endothelial lining which in places divides to form masses of round cells. These cells are calls Megaloblasts. They start acquiring Hb and are know as Erythroblasts.

You must also Read:
FAQs on Ayurveda
FAQs on Root Canal Therapy
CAUSES OF ABORTION DURING EARLY PREGNANCY
They become free in blood-stream, and finally about the mid-foetal life lose their nuclei to become non-nucleated discs.

Mid-foetal life to about 1 month before birth – As foetal development proceeds, the endothelial lining of vascular channels of the liver and the spleen divides and forms nucleated red cells. In acute haemopoietic crisis they may resume this function even after birth.

After birth – Red-cell formation takes place in red bone marrow. Its vascular bed is a meshwork of small blood sinuses called sinusoids lined by thin endothelium. A large number of these intercommunicating sinusoids are normally collapsed & quite impermeable to blood. Others are widely dilated, but owing to the vessels which lead to from them being contricted, they are isolated from the general circulation. Regions of low oxygen tension are thus produced, which serve as stimuli to formation of red cells. It is these collapsed inter-sinusoidal capillaries of ‘Sabin’ where erythropoiesis occurs after birth. Plasma filters in from adjacent capillaries & sweeps into circulation the newly formed red cells. The collapsed capillaries open up as soon as normoblasts have lost their nuclei.

  1. In the final stage of maturation the nuclei break up into fragments and disappear, leaving young red cellsThe cells are larger in number and the diameter of a cell varies from 5.5 to 8.8 (mean diameter is 7.3). Shape may be circular or bi-concave, when it is viewed from side, it looks like a dumb-bell. Average thickness is 2.2. Average surface is 120 sq.

    Functions of R.B.C. : (i) It maintains ionic balance and acid – base balance. (ii) It help to maintain viscosity of blood. (iii) Various pigments are derived from haemoglobin after the disintegration of the red cells, e.g. bilirubin, biliverdin etc. (iv) It helps respiration by carrying O2 and CO2.

    Development of R.B.C. : Development process of R.B.C. is Reticulo-Endothelial Cells – Haemocytoblast – Pro-erythroblast – Early normoblast – Late normoblast – Reticulocyte – Erythrocyte.

    Normal total count of R.B.C. : (i) In infants: 6 to 7 million/cu. mm. (ii) In adult male : 5 to 6 million / cu.mm. (iii) In adult female : 4 to 5 million / cu. mm. (iv) In foetus : 7 to 8 million / cu.mm.

    .

    Below Articles may be helpful to you:
    FAQs on DIARRHEA
    FAQs on ASTHMA
    FAQs on HEPATITIS

Ask our Counsellors


Comments

0 # Rohan 2018-08-07
Hii can you plz tell me, Which fluids can cause or spread syphilis infection, alos give me the list of good gynec in Patiala?
Reply | Reply with quote | Quote
0 # Dr. Pooja 2018-08-08
Infection from semen, blood or lactation milk can occur and cause syphilis, Infection from blood syringes is very common, Infected mothers can transmit it through their milk also, consult with good Gynecologist in Patiala .
Reply | Reply with quote | Quote
0 # Himmat 2018-07-31
Hii, I am from Firozabad, I want to know can cigerrete sharing can lead to syphilis ?
Reply | Reply with quote | Quote
0 # Dr. Naresh 2018-08-01
yes,sharing cigerette,drinking cups,common spoons etc can also lead to syphilis, Generally whenever the fluid of a person who has syphilis is shared,the infection can occur, you should also consult with good Gynecologist in Firozabad
Reply | Reply with quote | Quote
0 # Harikiran 2018-07-03
Hi, plz let me know What is the incubation period of Syphilis, also give me the list of good female's specialist in Karimnagar ?
Reply | Reply with quote | Quote
0 # Dr. Pooja 2018-07-04
Hii, The incubation period can be 10 to 90 days, plz find list of Gynecologist in Karimnagar
Reply | Reply with quote | Quote
0 # Harikiran Older than three months
Hello, plz tell me what are venereal diseases, can you plz suggest some good gynecologist in Goalpara ?
Reply | Reply with quote | Quote
0 # Dr. Pooja Older than three months
veneral diseases are those which can be spread through sexual contact, The spreading agents can bacteria ,viruses etc, The examples are syphilis and gonorrhoea can be can spread by sexual contact, you can also find list of Gynecologist in Goalpara.
Reply | Reply with quote | Quote
0 # Tushar Older than three months
Hii, can you plz tell me,What changes can occur in skin in syphilis patient, also suggest good obstertrician in Mahoba ?
Reply | Reply with quote | Quote
0 # Dr. Pooja Older than three months
Rashes can occur on the skin in the near areas,rashes can be discrete and also symmetrical in nature, Rashes can also be pustular, you can consult with Obstetrician in Mahoba.
Reply | Reply with quote | Quote
0 # Jayesh Older than three months
Hii, plz tell me,Which tests can confirm syphilis in primary stage, also suggest name of good maternity hospitals in Tuticorin ?
Reply | Reply with quote | Quote
0 # Dr. Pooja Older than three months
During the primary stage,DG illumination tests are very helpful, find good maternity hospitals-AVM Hospital ; Kamala Hospitals - Kovilpatti.
Reply | Reply with quote | Quote
0 # Aayush Older than three months
Hi, plz let me know What is the incubation period of Syphilis, also give me the list of good female's specialist in Darrang ?
Reply | Reply with quote | Quote
0 # Dr. Pooja Older than three months
Hii, The incubation period can be 10 to 90 days, plz find list of Gynecologist in Darrang
Reply | Reply with quote | Quote
0 # Vaibhav Older than three months
Hii, can you plz tell me,What changes can occur in skin in syphilis patient, also suggest good obstertrician in Auraiya ?
Reply | Reply with quote | Quote
0 # Dr. Naresh Older than three months
Rashes can occur on the skin in the near areas,rashes can be discrete and also symmetrical in nature, Rashes can also be pustular, you can consult with Obstetrician in Auraiya.
Reply | Reply with quote | Quote
0 # Harikiran Older than three months
Hii, I am from Prakasam, can you plz tell me What is the mode of infection in syphilis ?
Reply | Reply with quote | Quote
0 # Dr. Naresh Older than three months
90 percent cases in syphilis are transmitted through unsafe sexual contacts, Mothers can also pass infection through breast milk, you can also consult with good Gynecologist in Prakasam .
Reply | Reply with quote | Quote
0 # Vivaan Older than three months
Hii, plz tell me,Which tests can confirm syphilis in primary stage, also suggest name of good maternity hospitals in Central Delhi ?
Reply | Reply with quote | Quote
0 # Dr. Pooja Older than three months
During the primary stage,DG illumination tests are very helpful, find good maternity hospitals-Jeewan Mala Hospital ; Nijhara Hospital Private Limited ; Dr Sharma Child and Maternity Clinic ; K K Surgical and Maternity Center - Delhi.
Reply | Reply with quote | Quote