Frequently Asked Questions (FAQs) on myxoedema-hypothyroidism | HospitalKhoj

MYXOEDEMA (Hypothyroidism)

MYXOEDEMA (Hypothyroidism)

Ques. 1  What is Myxoedema?

Ans.       It is a diseased condition occurring in adults, marked by a thickening of sub-cutaneous tissue. It may occur endemically or sporadically.

Causes: Sex-commonly female, Age-mostly middle age.

  1. Prolonged iodine therapy.
  2. Idiopathic thyroid fibrosis.
  3. Hashimoto’s disease.
  4. Simmond’s disease.

Ques. 2  What is the Pathology of Myxoedema?

Ans.       The thyroid is small and hard with replacement of fibrosis. There is a protein infiltration of skin and sub-cutaneous tissue :- mucous membranes of the nasopharynx, mouth and ear also in larynx and oesophagus. Coronary blood vessels are sometimes atheromatous and heart is dilated. Testes/ovaries atrophy.


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Ques. 3  What are the symptoms and signs of Myxoedema?

Ans.       Symptoms –

  • Dryness and roughness of skin.
  • Pain in muscles and joints, clumsy gait, rheumatism.
    • Constipation or obstipation.
  • Dyspnoea, orthopnoea, dizziness.
  • Menometrorrhagia, may be amenorrhoea or sterility or habitual abortion.
  • Polyuria with nocturia.
  • Slowness of thought, loss of memory, drowsiness, hallucination.
  • Sometimes obese inspite of diminished appetite.
  • Headache, deafness, decreased visual acuity, ataxia, convulsion, facial neuralgia and coma.
  • Weakness and lethargy.
  • Low temperature, always require covering, prefer warm weather and room.
  • Pallor of skin.
  • Vertigo, tinnitus impaired hearing, chronic hoarseness or sinusitis.
  • Signs :

  • Skin thick, rough, dry and scaly on extremities.
  • Moderate obesity, non-pitting oedema.
  • Teeth may decay rapidly.
  • Thyroid usually small and hard to palpate.
  • Heat sounds slow (40 to 60 p.m.), distant, muffled.
  • Hypotension in early stage ; hypertension may develop later.
  • Diminished deep tendon reflexes.
  • Puffy features, ‘apple-blossom’ cheeks.
  • Slow speech with leathery, deep, hollow tones.
  • Hair dry, sometimes baldness.
  • Body temperature low (95°F).
  • Ques. 4  How can we Diagnose Myxoedema?

    Ans.       Diagnosis:

  • Butonol extractable iodine-low.
  • Serum cholesterol level-high.
  • Urinary 17-ketosteroids-usually low.
  • Glucose tolerance test-curve tends to be low & flat.
  • E.C.G.-bradycardia.
  • B.M.R. – low.
  • Serum protein-bound jodine-low.
  • Radioactive iodine uptake-low.
  • Differential:

  • Coronary infarction and insufficiency.
  • Pituitary myxoedema.
  • Chronic nephritis.
  • Treatment:

  • Thyroxine-Initial dose 0.25 mg. daily gradually increased to minimum maintenance dose.
  • Laevo-thyroxine sodium (Eltroxin) – Initial does 0.05 mg. daily, gradually increased to minimum maintenance dose.
  • Ventilatory assistance and steroid may be given.
  • Treatment is to be continued all throughout life.
  • Symptomatic treatment.
  • Homoeopathic remedies.
  • THYROIDINUM – Weakness. Easy fatigue, tendency to fainting, palpitation, cold bands and feet, low blood pressure, chilliness and sensitive to cold, weak pulse.

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    0 # Vaibhav 2018-08-05
    Hello, plz tell me what are venereal diseases, can you plz suggest some good gynecologist in Dibang Valley ?
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    0 # Dr. Pooja 2018-08-06
    veneral diseases are those which can be spread through sexual contact, The spreading agents can bacteria ,viruses etc, The examples are syphilis and gonorrhoea can be can spread by sexual contact, you can also find list of Gynecologist in Dibang Valley.
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    0 # Jayesh 2018-07-29
    My friend has been diagnosed with gonorrhoea, Please tell which tests will be advisable, also suggest gynec in Etawah ?
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    0 # Dr. Naresh 2018-07-30
    VDRL tests should be done every month for 3 consecutive months for detecting syphilis as well as other sexually transmitted diseases,These tests should be conducted at proper times, find good Gynecologist in Etawah
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    0 # Aayush Older than three months
    Hii, I am from Baramulla, I want to know can cigerrete sharing can lead to syphilis ?
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    0 # Dr. Pooja Older than three months
    yes,sharing cigerette,drinking cups,common spoons etc can also lead to syphilis, Generally whenever the fluid of a person who has syphilis is shared,the infection can occur, you should also consult with good Gynecologist in Baramulla
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    0 # Aarush Older than three months
    Hii can you plz tell me, Which fluids can cause or spread syphilis infection, alos give me the list of good gynec in Imphal West?
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    0 # Dr. Pooja Older than three months
    Infection from semen, blood or lactation milk can occur and cause syphilis, Infection from blood syringes is very common, Infected mothers can transmit it through their milk also, consult with good Gynecologist in Imphal West .
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    0 # Priyansh Older than three months
    Can gonorrhoea be caused by the infected towels, also provide the list of good gynecologist in Lucknow?
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    0 # Dr. Pooja Older than three months
    Gonorrhoea can be transmitted by the infected towels, handkerchiefs of the infected person, But most cases are due to sexual contacts, find here list of good Gynecologist in Lucknow.
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