Dent's disease - Some Details To Know

Dent's disease - Some Details To Know

Dent’s Disease, which is otherwise called as Dent disease is a chronic issue associated with kidney and it is known to be highly common in men as against women. In affected individuals, kidney related issues result from spoilage to structures known as proximal tubules. Experts are of the opinion that the signs and symptoms of this condition generally occurs in early childhood and become worse as years pass by.

Signs of Dent Disease:

The most known sign of this disorder is the presence of an excessive amount of protein the urine. Here are the other symptoms:

• Hypercalciuria, which means higher level of calcium content in the urine

• Nephrocalcinosis, which means higher level of calcium deposits in the kidneys.

• Nephrolithiasis, which denotes kidney stones, which in turn can cause ache in abdomen and blood in urine.

• Some patients also experience rickets. This is a disorder associated with bones that occur when the body has very lesser level of Vitamin D and other minerals like calcium. This can also lead to difficulty in walking, bowed legs, bone pain and bone weakness.

In most of the affected men, ever-improving problems associated with kidneys lead to end-stage renal disease. This condition is shortly called as ESRD and it generally occurs in early or in the middle adulthood period. This condition is stated to be renal failure, which can cause threats to the life and it occurs when the kidneys are unable to filter fluids and unwanted content from the body anymore.

Two types of dent disease:

Two forms of Dent disease are found by researchers and these two types differ in their genetic cause, pattern, signs and symptoms. These are type 1 and Type 2 and both these types can cause the symptoms mentioned above. On the other hand, the type 2 dent disease can showcase abnormalities that are not related to kidney function. What are those additional signs?

• Cataract, which does not impair vision

• Hypotonia, which means weak muscles

• Mile intellectual disability

Researchers state that type 2 dent disease has a mild variation when compared to the similar disorder known as Lowe Syndrome.

How common is this disorder?

This is a rare condition and of the two types of this disease, the type 1 is more common as against the type 2. There are great chances that this disease can be under-diagnosed as it may not be diagnosed in people with mild symptoms, signs and its features overlap with other renal disorders.

What is the treatment given for this condition?

The fact is that at present, there is not any recognized treatment for this disease and there are no therapies available as well. However, supportive medicines are prescribed for patients to manage the troubles caused by this disease. These medicines include:

• Even though, thiazide diuretics are used with a view to bring down the level of calcium in urine, this medicine is known to cause low level of potassium in blood.

• For idiopathic hypercalciuria, which means for calcium in urine without any cause, Amiloride is prescribed.

• For patients with bone disease, Vitamin D supplements are prescribed.

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# Vaibhav 2017-04-13
Hii, plz tell me,Which tests can confirm syphilis in primary stage, also suggest name of good maternity hospitals in Raichur ?
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