Hyperlipidemia - Some Details To Know

Have you heard about Hyperlipidemia earlier? This is nothing, but a condition that is characterized by heightened concentrations of circulating lipids. When this happens, there will be an increase in the risk of atherosclerosis and many other serious conditions. Some specific classes of this condition include heightened triglyceride levels, heightened cholesterol levels, heightened low-density lipoprotein levels and heightened very low-density lipoprotein. These four classes are denoted by appropriate medical terms.

In general, the medical history and lifestyle are taken into consideration when a health care provider assesses the lipid profile. Generally, the test is done when a patient is in a steady state without any acute illness or significant change in weight. Also, when diagnosing this condition, medications taken by the patient for other health issues will also be considered by the doctor. The reason is that medications can interfere in lipid metabolism.

Laboratory testing:

The patient will be recommended to fast at least for 12 hours before taking blood samples. The reason is chylomicron clearance can take a maximum of 10 hours. This is required only for identifying this condition, but fasted sample is not important when it comes to simple cholesterol screening.

Lab test will involve lipid profile for measuring the total plasma cholesterol, triglyceride level and HDL levels. The VLDL will be arrived at by dividing the triglyceride value by 5. When this is the case of VLDL, LDL will be arrived at by subtracting the VLDL and HDL from total cholesterol level.

How is the condition detected?

This condition does not typically show up any symptoms and so doctors detect this condition during routine physical examination. In some patients this turns out to be familial condition and it will be possible to find fatty deposits under their skin surface to identify this medical condition.


This condition is often the result of defective or delayed clearance or over production of very low-density lipoprotein (VLDL) by the liver. This is then transformed into low-density lipoprotein (LDL). When an individual consumes excess saturated fats, the liver will produce more of VLDL and triglycerides through a molecular mechanism that involves protein activators. In general, this particular fat content that increases in the VLDL level can be found in dairy products and other animal products like meat and also in tropical oils like coconut, palm kernel and palm.

What is the health risk?

When there is heightened LDL or high-density lipoprotein, there will be risk of heart attack both in men and women. When it comes to heightened triglyceride levels, it is known to be riskier in female patients.

Risk factors:

As compared to women, this condition is known to be common in men and here are the other risk factors involved:

• Smoking

• Oral contraceptives

• Usage of steroid

• Alcoholism

• Physical activity

• Obesity

• Hypothyroidism

• Hypopituitarism

• Nephrotic syndrome

• Chronic renal failure

• Metabolic syndrome and diabetes

• Diet that are rich in saturated and total fat content

• Family history

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